Dog Supplement
Reviews and Ratings

Science-backed insights and honest reviews to help you choose the best supplements for your dog

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Featured Reviews

Our most popular dog supplement reviews this month! Whether you’re looking to support your dog’s joints, digestion, immune system, or overall wellness, we’ve highlighted top-rated products to help you make informed choices.

  • Nutramax Dasuquin with MSM

    Ingredient Transparency:

    5 / 5

    Scientific Support:

    4.5 / 5

    Brand Score:

    5 / 5

    overall Rating:

    4.5 / 5

    Read Review

    Product Overview

    Dasuquin with MSM delivers exceptional joint support using a scientifically backed formula featuring ASU. While the premium cost and frustration with packaging durability are valid concerns, the strict quality control and documented efficacy make it a reliable, top-tier choice for maintaining canine mobility and comfort long term.

    Key Benefits

    • Helps inhibit cartilage breakdown with clinically backed ASU.
    • NASC Seal verifies quality standards and label accuracy.
    • MSM supports comfort and a normal inflammatory response.
    • Promotes long-term mobility for active dogs.

    Pros

    • Formula utilizes the clinically supported, unique ASU ingredient.
    • Strict manufacturing quality control ensures total product consistency.
    • Trusted and widely recommended by veterinary professionals.

    Cons

    • Significantly higher price point than generic competitors.
    • Requires weeks of consistent use for results.
    • Resealable bag zipper frequently fails to close.

    Bottom line

    This supplement sets the gold standard for joint health with its research-backed ingredients and rigorous testing. Despite the high price tag, the long-term benefits for mobility make it a worthwhile investment for aging or active dogs requiring reliable, safe, and effective structural support for daily comfort.

  • Pet Honesty Multivitamin 10-in-1

    Ingredient Transparency:

    4 / 5

    Scientific Support:

    3.5 / 5

    Brand Score:

    4 / 5

    overall Rating:

    4 / 5

    Read Review

    Product Overview

    Pet Honesty Multivitamin 10-in-1 is a soft chew that bundles joint, gut, skin, and general wellness support with strong palatability and NASC aligned quality, but modest doses and limited product specific research mean results are usually subtle and not guaranteed for every dog.

    Key Benefits

    • Supports everyday joint, gut, skin wellness
    • Simple all in one daily routine
    • Soft chews that most dogs enjoy
    • Best for mild, mixed wellness needs

    Pros

    • Transparent label and quality seal
    • Easy, palatable soft chew format
    • Combines several research backed ingredients

    Cons

    • Some ingredient amounts may be lower than study levels
    • Not essential for healthy dogs on AAFCO-approved diet
    • No clinical trials for this specific formula

    Bottom line

    A convenient, tasty soft chew that offers light daily wellness support for many dogs, but with moderate dosing and limited direct research, it is best viewed as a helpful extra rather than a treatment for specific conditions.

  • Flexadin Advanced with UCII

    Ingredient Transparency:

    4 / 5

    Scientific Support:

    4 / 5

    Brand Score:

    4.5 / 5

    overall Rating:

    4 / 5

    Read Review

    Product Overview

    Flexadin Advanced with UC-II helps dogs move easier by reducing joint inflammation through immune balance. This once-daily chew uses patented undenatured collagen with vitamin E for comfort and mobility. It’s research-backed, well tolerated, and ideal for long-term support in dogs with mild to moderate joint stiffness.

    Key Benefits

    • Supports joint comfort and flexibility through UC-II.
    • Reduces stiffness and promotes easier movement.
    • Enhances long-term mobility and quality of life.
    • Simple once-daily chew for consistent use.

    Pros

    • Improves mobility and overall comfort.
    • Safe for long-term daily use.
    • Easy to give and well accepted.

    Cons

    • Takes weeks for results to appear.
    • Costs more than basic supplements.
    • Not ideal for dogs with chicken allergies.

    Bottom line

    Flexadin Advanced with UC-II offers proven joint relief through a unique immune-tolerance pathway. Backed by veterinary research and owner satisfaction, it’s a smart, convenient choice for managing mild to moderate arthritis and keeping dogs active, comfortable, and playful with consistent daily use.

  • Fera Pets Hip + Joint Support

    Ingredient Transparency:

    4.5 / 5

    Scientific Support:

    4.5 / 5

    Brand Score:

    5 / 5

    overall Rating:

    4.5 / 5

    Read Review

    Product Overview

    Fera Pets Hip + Joint Support offers a vet-formulated blend of Green Lipped Mussel, Glucosamine Sulfate, and BioPerine. While the chicken bone broth flavored chews are designed to support a healthy inflammatory response and carry the NASC Quality Seal, we found during testing that they can be fragile and crumble easily inside the jar.

    Key Benefits

    • Helps maintain healthy cartilage and joint fluid
    • Green Lipped Mussel supports a healthy inflammatory response
    • Intended to support mobility for active dogs
    • BioPerine is included to help with turmeric absorption

    Pros

    • Ingredient quantities verified by the NASC Quality Seal
    • Includes BioPerine black pepper for absorption
    • Free from common fillers like corn, soy, and grain
    • Tasty chicken bone broth flavor

    Cons

    • Chews crumble easily in jar
    • Strong marine smell lingers
    • Rich oils may cause loose stools
    • Contains shellfish allergens

    Bottom line

    This supplement is a solid choice for owners seeking a multimodal joint supplement. It balances high-quality ingredients like Green Lipped Mussel with verifiable safety standards. Despite minor texture issues like crumbling, the concentrated, vet-formulated formula offers consistent value for any aging or active large breed dog.

  • Wuffes Advanced Hip & Joint Support

    Ingredient Transparency:

    4.5 / 5

    Scientific Support:

    4 / 5

    Brand Score:

    4.5 / 5

    overall Rating:

    4.5 / 5

    Read Review

    Product Overview

    Wuffes combines Glucosamine and Green-Lipped Mussel to support joint health. It carries the trusted NASC seal and offers tailored formulas for both small and large breeds. While it uses Glucosamine in HCl form, it remains a reliable, tasty option for supporting mobility in dogs of any age

    Key Benefits

    • Supports healthy cartilage structure with Glucosamine
    • Helps support normal inflammatory response with Green-Lipped Mussel
    • Helps maintain joint lubrication using Chondroitin Sulfate
    • Maintains connective tissue health with Manganese

    Pros

    • Verified NASC quality safety seal
    • High potency for weight class
    • Tasty formula with high acceptance
    • Includes Omega-3s and GLM

    Cons

    • Glucosamine HCl form may be less proven than Sulfate form
    • Takes weeks to show full results
    • Higher price than generic brands
    • Pork flavor may trigger allergies

    Bottom line

    Wuffes offers a safe, concentrated solution for canine joint stiffness. With specific formulas for small and large dogs, it provides effective structural nutrients and anti-inflammatories. Although expensive, the verified purity and potent dosing options provide excellent value for owners seeking reliable, long-term support.

The Complete Guide to Dog Supplements

Do dogs really need supplements? We break down the evidence behind probiotics, multivitamins, and joint support. Learn how to identify safe products and integrate them into your dog’s wellness strategy.

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